KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRB7
All Species:
19.7
Human Site:
Y492
Identified Species:
54.17
UniProt:
Q14451
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14451
NP_001025173.1
532
59681
Y492
S
E
E
E
G
R
L
Y
F
S
M
D
D
G
Q
Chimpanzee
Pan troglodytes
XP_001171807
532
59632
Y492
S
E
E
E
G
R
L
Y
F
S
M
D
D
G
Q
Rhesus Macaque
Macaca mulatta
XP_001091612
532
59697
Y492
S
E
E
E
G
R
L
Y
F
S
M
D
D
G
Q
Dog
Lupus familis
XP_548141
530
59153
Y490
S
E
E
E
G
R
L
Y
F
S
M
D
D
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q03160
535
59941
Y495
S
E
D
E
G
C
L
Y
F
S
M
D
E
G
Q
Rat
Rattus norvegicus
P0CE43
599
67864
F559
C
E
D
D
G
Q
T
F
F
T
L
D
D
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506127
625
71314
F585
C
E
D
D
G
Q
M
F
F
S
L
D
D
G
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCV1
653
72662
S566
P
S
P
P
S
F
M
S
N
A
E
N
P
P
P
Zebra Danio
Brachydanio rerio
Q6PFT9
646
70983
S551
F
L
P
P
P
P
P
S
F
V
S
H
G
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
93.4
N.A.
90.2
48.9
N.A.
46.5
N.A.
22.3
22.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
98.8
95.4
N.A.
93
66.4
N.A.
61.2
N.A.
35.2
37
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
40
N.A.
46.6
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
80
N.A.
86.6
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% A
% Cys:
23
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
23
0
0
0
0
0
0
0
78
67
0
0
% D
% Glu:
0
78
45
56
0
0
0
0
0
0
12
0
12
0
12
% E
% Phe:
12
0
0
0
0
12
0
23
89
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
78
0
0
0
0
0
0
0
12
89
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
0
0
56
0
0
0
23
0
0
0
0
% L
% Met:
0
0
0
0
0
0
23
0
0
0
56
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
23
% N
% Pro:
12
0
23
23
12
12
12
0
0
0
0
0
12
12
12
% P
% Gln:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
56
% Q
% Arg:
0
0
0
0
0
45
0
0
0
0
0
0
0
0
0
% R
% Ser:
56
12
0
0
12
0
0
23
0
67
12
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _